How Much Does Hydrochlorothiazide + Lisinopril Cost in Mexico vs the USA?
Sold in Mexico as Zestoretic Lisinopril 20Mg 14 Tabs, Zestoretic Lisinopril 20Mg 28 Tabs, ZESTORETIC 20/12.5MG. Also known by the brand name Zestoretic.
About Hydrochlorothiazide + Lisinopril
Lisinopril Hydrochlorothiazide combines two medications: lisinopril, which helps relax blood vessels, and hydrochlorothiazide, a diuretic that reduces water retention. This combination is commonly used to help manage blood pressure, promoting better blood flow and overall cardiovascular health.
Prices updated:
Available Strengths
Price per unit is fairly stable across doses.
Price per unit by strength (generic)
Showing pharmacy listings for 12.5mg
Generic pricing — 12.5mg
United States
generic$38.95$5.27with pharmacy coupon$0.18 / unit
generic$38.95$5.27with pharmacy coupon$0.18 / unit
generic$38.95$5.88with pharmacy coupon$0.20 / unit
generic$38.95$5.88with pharmacy coupon$0.20 / unit
generic$38.95$9.59with pharmacy coupon$0.32 / unit
generic$38.95$13.15with pharmacy coupon$0.44 / unit
generic$38.95$18.90with pharmacy coupon$0.63 / unit
generic$38.95$19.11with pharmacy coupon$0.64 / unit
In the USA, the generic and brand-name product are priced about the same.
Brand-name pricing — 12.5mg
United States
- Zestoreticbrand$38.95$5.27with pharmacy coupon$0.18 / unit
- Zestoreticbrand$38.95$5.27with pharmacy coupon$0.18 / unit
- Zestoreticbrand$38.95$5.88with pharmacy coupon$0.20 / unit
- Zestoreticbrand$38.95$5.88with pharmacy coupon$0.20 / unit
- Zestoreticbrand$38.95$9.59with pharmacy coupon$0.32 / unit
- Zestoreticbrand$38.95$13.15with pharmacy coupon$0.44 / unit
- Zestoreticbrand$38.95$18.90with pharmacy coupon$0.63 / unit
- Zestoreticbrand$38.95$19.11with pharmacy coupon$0.64 / unit
Showing pharmacy listings for 20mg
Generic pricing — 20mg
Mexico
Prices range $34.58–$60.75 between pharmacies we track — worth comparing.
Zestoretic 20 Mg 14 Tabgeneric$34.58$2.47 / unit
Zestoretic Lisinopril 20Mg 14 Tabsgeneric$36.44$2.60 / unit
Zestoretic 20 mg Oral 14 Tabsgeneric$42.95$3.07 / unit- Zestoretic 20 Mg 28 Tabgeneric$50.33$1.80 / unit
- Zestoretic 20Mg 28 Tabsgeneric$51.29$1.83 / unit
- Zestoretic Lisinopril 20Mg 28 Tabsgeneric$58.59$2.09 / unit
- Zestoretic 20 mg Oral 28 Tabsgeneric$60.75$2.17 / unit
In Mexico, the generic saves you 4.5% vs the brand-name product.
Brand-name pricing — 20mg
Mexico
Prices range $37.01–$62.38 between pharmacies we track — worth comparing.
ZESTORETIC 20MG TAB CAJ C/14brand$37.01$2.64 / unit
Zestoretic 20 Mg Tabletas 14 Pzbrand$40.09$2.86 / unit- ZESTORETIC 20MG TAB CAJ C/28brand$52.13$1.86 / unit
- Zestoretic 20 Mg 28 Tabletas 28 Pzbrand$62.38$2.23 / unit
Showing pharmacy listings for 20mg + 12.5mg
Brand-name pricing — 20mg + 12.5mg
Mexico
Prices range $42.42–$64.25 between pharmacies we track — worth comparing.
- ZESTORETIC 20/12.5MG TAB CAJ C/14brand$42.42$3.03 / unit
Zestoretic 20/12.5mg con 28 Tabletasbrand$53.61$1.91 / unit- ZESTORETIC 20/12.5MG TAB CAJ C/28brand$64.25$2.29 / unit
Showing pharmacy listings for 20mg + 12.5mg
Generic pricing — 20mg + 12.5mg
Mexico
Prices range $28.88–$48.52 between pharmacies we track — worth comparing.
Zestoretic 20mg/12.5mg 14 Tabletas.generic$28.88$2.06 / unit- Zestoretic 20mg/12.5mg, 28 Tabletas.generic$48.52$1.73 / unit
In Mexico, the generic saves you 17.9% vs the brand-name product.
Brand-name pricing — 20mg + 12.5mg
Mexico
Prices range $35.71–$66.17 between pharmacies we track — worth comparing.
Zestoretic 20 mg / 12.5mg caja 14 tabletasbrand$35.71$2.55 / unit
Tabletas Zestoretic 20mg/12.5mg Caja con 14 Tabletasbrand$37.64$2.69 / unit
Zestoretic 14 Tabletas Caja Lisinopril dihidratado 20 MG Hidroclorotiazida 12.5 MGbrand$42.42$3.03 / unit- Tabletas Zestoretic 20mg/12.5mg Caja con 28 Tabletasbrand$44.43$1.59 / unit
- Zestoretic 20 mg / 12.5mg caja con 28 tabletasbrand$46.51$1.66 / unit
- Zestoretic 28 Tabletas Caja Lisinopril dihidratado 20 MG Hidroclorotiazida 12.5 MGbrand$64.25$2.29 / unit
Zestoretic 20 mg Lisinopril/12.5 mg Hidroclorotiazida 28 Tabletasbrand$66.17$2.36 / unit
Showing pharmacy listings for 20mg + 12.5mg + 20mg + 12.5mg
Brand-name pricing — 20mg + 12.5mg + 20mg + 12.5mg
- ZESTORETIC 20/12.5MG - TAB 28 Lisinopril 20 mg, Hidroclorotiazida 12.5 mg Caja cbrand$56.31
Similar Medications
Frequently Asked Questions
Is there a generic version of Lisinopril Hydrochlorothiazide?
Yes, Lisinopril Hydrochlorothiazide is available both as a brand-name product and as a generic.
How can I save money on Lisinopril Hydrochlorothiazide?
Compare prices for Lisinopril Hydrochlorothiazide across Mexican and US pharmacies above to find the lowest price, and check whether a generic version is available - generics are typically cheaper than the brand-name product.
Data & Disclaimers
Prices last checked: August 8, 2026.
Prices are collected periodically from pharmacy websites and public pricing sources and are shown for general reference only — actual prices can vary by pharmacy, location, and over time. Frontera Rx is not a pharmacy and does not sell medication; we don't provide medical advice. Always confirm the current price and availability with the pharmacy before you buy or travel. Read our full disclaimer.
*NADAC markup is a reference figure: how many times higher a US retail price is than the National Average Drug Acquisition Cost (NADAC), a public wholesale benchmark published by the US government. It reflects one factor in how US retail drug prices are set; we show it as neutral background information, not as a judgment about any pharmacy or program. For this product, the US retail price runs about 35.0× the NADAC reference.