How Much Does Orphenadrine Cost in Mexico vs the USA?
Prices updated:
Available Strengths
Price per unit varies noticeably between doses — worth comparing.
Price per unit by strength (generic)
Showing pharmacy listings for 2ml + 30mg ampule
Generic pricing — 2ml + 30mg ampule
United States
generic$21.98$17.94with pharmacy coupon$8.97 / unit
generic$21.98$17.94with pharmacy coupon$8.97 / unit
generic$21.98$10.99 / unit
generic$21.98$10.99 / unit
generic$21.98$10.99 / unit
generic$21.98$10.99 / unit
generic$21.98$10.99 / unit
Showing pharmacy listings for 35mg + 450mg tablet
Generic pricing — 35mg + 450mg tablet
Mexico
Prices range $38.83–$42.29 between pharmacies we track — worth comparing.
Norflex Plus 35/450 Mg Tab 50generic$38.83
Norflex Plus 35Mg/450Mg 50 Tabsgeneric$41.07$0.82 / unit
Norflex Plus 35/450 mg Oral 50 tabletasgeneric$42.29$0.85 / unit
In Mexico, the generic saves you 5.5% vs the brand-name product.
Brand-name pricing — 35mg + 450mg tablet
Norflex Plus 35/450 Mg 50 Tab 50 Pzbrand$44.12$0.88 / unit
Showing pharmacy listings for 100mg tablet
Generic pricing — 100mg tablet
United States
- generic$21.96$18.12with pharmacy coupon$0.91 / unit
- generic$21.96$18.12with pharmacy coupon$0.91 / unit
- generic$21.96$15.66with pharmacy coupon$0.78 / unit
generic$21.96$18.80with pharmacy coupon$0.94 / unit- generic$21.96$1.10 / unit
- generic$21.96$1.10 / unit
- generic$21.96$1.10 / unit
- generic$21.96$1.10 / unit
- generic$21.96$1.10 / unit
Showing pharmacy listings for 450mg + 35mg capsule
Generic pricing — 450mg + 35mg capsule
Mexico
Prices range $29.69–$36.94 between pharmacies we track — worth comparing.
Norflex Plus GB 450mg/35mg, 30 Cápsulas.generic$29.69$0.99 / unit- Norflex Plus Gb 450/35Mg 30Capgeneric$33.06$1.10 / unit
- Norflex Plus Gb 450Mg/35Mg 30 Capsgeneric$36.94$1.23 / unit
In Mexico, the brand-name product is actually about 11.2% cheaper than the generic here.
Brand-name pricing — 450mg + 35mg capsule
Norflex Plus GB 450/35mg con 30 Cápsulasbrand$29.88$1.00 / unit
Showing pharmacy listings for 450mg + 35mg tablet
Generic pricing — 450mg + 35mg tablet
Mexico
Prices range $32.83–$39.77 between pharmacies we track — worth comparing.
- Norflex Plus 450mg/35mg, 50 Tabletas.generic$32.83$0.66 / unit
Norflex Plus 50 tabletas 450 mg/35 mggeneric$33.73$0.67 / unit
Norflex Plus 450 mg/35 mg con 50 Tabletasgeneric$36.83$0.74 / unit
NORFLEX PLUS 450MG/35MG C/50 TABS.generic$39.77$0.80 / unit
In Mexico, the brand-name product is actually about 2.8% cheaper than the generic here.
Brand-name pricing — 450mg + 35mg tablet
Mexico
Prices range $33.06–$36.59 between pharmacies we track — worth comparing.
- Norflex Plus 450/35mg con 50 Tabletasbrand$33.06$0.66 / unit
Norflex Plus 450mg/ 35mg Frasco Con 50 Tabletasbrand$36.59$0.73 / unit
FDA Drug Information
Official prescribing information for ORPHENADRINE CITRATE
Excerpted from the FDA-approved label (Northwind Health Company, LLC) — not medical advice. Always read the full label and talk to a pharmacist or doctor before use.
What It's Used For
INDICATIONS AND USAGE Orphenadrine citrate extended-release tablets are indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute painful musculoskeletal conditions.
Dosage & Administration
DOSAGE AND ADMINISTRATION Adults Two tablets per day; one in the morning and one in the evening.
Contraindications
CONTRAINDICATIONS Orphenadrine citrate extended-release tablets are contraindicated in patients with glaucoma, pyloric or duodenal obstruction, stenosing peptic ulcers, prostatic hypertrophy or obstruction of the bladder neck, cardio-spasm (mega-esophagus) and myasthenia gravis. Orphenadrine citrate tablets are…
Warnings
WARNINGS Some patients may experience transient episodes of light-headedness, dizziness or syncope. Orphenadrine may impair the ability of the patient to engage in potentially hazardous activities such as operating machinery or driving a motor vehicle; ambulatory patients should therefore be cautioned accordingly.
Possible Side Effects
ADVERSE REACTIONS Adverse reactions of orphenadrine are mainly due to the mild anticholinergic action of orphenadrine, and are usually associated with higher dosage. Dryness of the mouth is usually the first adverse effect to appear. When the daily dose is increased, possible adverse effects include: tachycardia,…
Pregnancy & Breastfeeding
Pregnancy Pregnancy Category C Animal reproduction studies have not been conducted with orphenadrine. It is also not known whether orphenadrine can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Orphenadrine should be given to a pregnant woman only if clearly needed.
Similar Medications
Other forms of Orphenadrine
Frequently Asked Questions
Is there a generic version of Orphenadrine?
Yes, Orphenadrine is available both as a brand-name product and as a generic.
How can I save money on Orphenadrine?
Compare prices for Orphenadrine across Mexican and US pharmacies above to find the lowest price, and check whether a generic version is available - generics are typically cheaper than the brand-name product.
Data & Disclaimers
Prices last checked: October 3, 2026.
Prices are collected periodically from pharmacy websites and public pricing sources and are shown for general reference only — actual prices can vary by pharmacy, location, and over time. Frontera Rx is not a pharmacy and does not sell medication; we don't provide medical advice. Always confirm the current price and availability with the pharmacy before you buy or travel. Read our full disclaimer.
*NADAC markup is a reference figure: how many times higher a US retail price is than the National Average Drug Acquisition Cost (NADAC), a public wholesale benchmark published by the US government. It reflects one factor in how US retail drug prices are set; we show it as neutral background information, not as a judgment about any pharmacy or program. For this product, the US retail price runs about 1.9× the NADAC reference.