We are not a pharmacy and do not sell medication. Prices are collected periodically and may have changed — always confirm the current price before you buy or travel.Read full disclaimer

How Much Does Systane Cost in Mexico vs the USA?

About Systane

Systane is a range of over-the-counter eye drops, ointments, and gels designed to provide relief for dry and irritated eyes. These products work by adding moisture to the eye's surface and helping to prevent evaporation, making them useful for those experiencing discomfort due to dryness or allergies.

8Mexican pharmacies tracked for this product

Prices updated:

Available Strengths

Showing pharmacy listings for 10ml

Generic pricing — 10ml

Mexico

Prices range $21.83–$52.86 between pharmacies we track — worth comparing.

High confidence · 11 pharmacies
Best price right now$21.83at FARMACIAS SIMILARES
  • FARMACIAS SIMILARES
    GOTAS LUBRICANTES OFTALMICAS 10ML SYSTANE ULTRAgeneric
    FARMACIAS SIMILARES· priced September 1, 2026
    $21.83
  • FARMACIAS GUADALAJARA
    Systane Ultra Gotas Lubricantes, 10 ml.generic
    FARMACIAS GUADALAJARA· priced September 1, 2026
    $33.60
  • VIDA FARMACIAS
    Systane Complete Gotas Oftálmicas Lubricantes Caja Con 10 mLgeneric
    VIDA FARMACIAS· priced September 1, 2026
    $34.31
  • WALMART
    Gotas Oftálmicas Systane lubricantes 10 mlgeneric
    WALMART· priced September 1, 2026
    $36.46
  • FARMACIAS GUADALAJARA
    Systane Ultra SP Gotas Oftálmicas Lubricantes, 10 ml.generic
    FARMACIAS GUADALAJARA· priced September 1, 2026
    $36.97
  • FARMACIAS GUADALAJARA
    Systane Ultra Plus Gotas Lubricantes, 10 ml.generic
    FARMACIAS GUADALAJARA· priced September 1, 2026
    $37.09
  • FARMACIAS GUADALAJARA
    Systane Balance 10 ml, Gotas Lubricantes.generic
    FARMACIAS GUADALAJARA· priced September 1, 2026
    $38.83
  • FARMACIAS GUADALAJARA
    Systane Complete 10 ml, Gotas Oftálmicas Lubricantes.generic
    FARMACIAS GUADALAJARA· priced September 1, 2026
    $40.28
  • FARMACIAS GUADALAJARA
    Systane Hidratación SP Gotas Oftálmicas, 10 ml.generic
    FARMACIAS GUADALAJARA· priced September 1, 2026
    $41.16
  • YZA FARMACIAS
    Gotas SYSTANE Balance 10mlgeneric
    YZA FARMACIAS· priced September 1, 2026
    $46.79
  • VIDA FARMACIAS
    Systane Complete Gotas Oftálmicas Lubricantes De 10 mLgeneric
    VIDA FARMACIAS· priced September 1, 2026
    $52.86

Brand-name pricing — 10ml

Mexico

Prices range $36.11–$47.32 between pharmacies we track — worth comparing.

Moderate confidence · 9 pharmacies
Best price right now$36.11at FARMACIAS BENAVIDES
  • FARMACIAS BENAVIDES
    Systane Ultra Gotas Lubricantes Oculares 10 mlbrand
    FARMACIAS BENAVIDES· priced September 1, 2026
    $36.11
  • CHEDRAUI
    Gotas Oftálmicas Systane Ultra Lubricantes Alto Desempeño Gotero con 10mlbrand
    CHEDRAUI· priced September 1, 2026
    $37.86
  • FARMACIAS BENAVIDES
    Systane Hidratación SP Gotas Oftálmicas Lubricantes con Ácido Hialurónico 10 mlbrand
    FARMACIAS BENAVIDES· priced September 1, 2026
    $38.80
  • CHEDRAUI
    Systane Ultra Plus Gotas 10mlbrand
    CHEDRAUI· priced September 1, 2026
    $38.97
  • FARMACIAS BENAVIDES
    Systane Ultra Plus Gotas Lubricantes Oculares 10 mlbrand
    FARMACIAS BENAVIDES· priced September 1, 2026
    $39.61
  • FARMACIAS BENAVIDES
    Systane Complete Gotas Oftálmicas Lubricantes 10 mlbrand
    FARMACIAS BENAVIDES· priced September 1, 2026
    $41.37
  • FARMACIAS BENAVIDES
    Systane Ultra SP Gotas Oftálmicas Lubricantes 10 mlbrand
    FARMACIAS BENAVIDES· priced September 1, 2026
    $44.63
  • FARMACIAS BENAVIDES
    Systane Complete Sp Gotas Oftálmicas Lubricantes 10 mlbrand
    FARMACIAS BENAVIDES· priced September 1, 2026
    $45.45
  • CHEDRAUI
    Gotas Lubricantes Oculares Systane Balance Frasco Gotero con 10mlbrand
    CHEDRAUI· priced September 1, 2026
    $47.32

Buying Systane in Mexico

New to cross-border pharmacy shopping? Our guide to buying medication in Mexico covers pharmacies, prescriptions, and payment. If you're planning to bring Systane back to the US, check first whether it's legal to bring this medication across the border.

Similar Medications

Frequently Asked Questions

Is there a generic version of Systane?

Yes, Systane is available both as a brand-name product and as a generic.

How can I save money on Systane?

Compare prices for Systane across Mexican and US pharmacies above to find the lowest price, and check whether a generic version is available - generics are typically cheaper than the brand-name product.

Data & Disclaimers

Prices last checked: September 1, 2026.

Prices are collected periodically from pharmacy websites and public pricing sources and are shown for general reference only — actual prices can vary by pharmacy, location, and over time. Frontera Rx is not a pharmacy and does not sell medication; we don't provide medical advice. Always confirm the current price and availability with the pharmacy before you buy or travel. Read our full disclaimer.